Absolutely doable.... and I soak the crap out of them, not mist 😅
All I do is tape off the charger port, but even that isn't necessary as most if not all new phones have moisture detection sensors and wont charge until the moisture is remove or has dissipated, thus not damaging the phone.
Have always done a premask and hand cut out for them, but software would be nice. Though its a great way to make some extra money off those small "scrap" pieces... I put scrap in quotes because the shit is so damn expensive, it hurts throwing any out 😂